Analytical Data
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基因名
GPRIN2
- Application
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别名
GPRIN2; KIAA0514G protein-regulated inducer of neurite outgrowth 2; GRIN2
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O60269
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表达区间
1-461aa
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氨基酸序列
MSSSHPEPGPWAPLSPRLQPLSQSSSSLLGEGREQRPELHKTASSTMWQAQLGEASTRPQAPEEEGNPPESMKPARASGPKARPSAGGHWRSSTVGNVSTMGGGDLCRLRAPSAAAMQRSHSDLVRSTQMRGHSGARKASLSCSALGSSPVHRAQLQPGGTSGQGGQAPAGLERDLAPEDETSNSAWMLGASQLSVPPLDLGDTTAHSSSAQAEPKAAEQLATTTCHALPPAALLCGMREMREVGAGGCCHALPATGILAFPKLVASVSESGLQAQHGVKIHCRLSGGLPGHSHCCAHLWGPAGLVPEPGSRTKDVWTMTSANDLAPAEASPLSAQDAGVQAAPVAACKAVATSPSLEAPAALHVFPEVTLGSSLEEAPSPVRDVRWDAEGMTWEVYGAAVDPEVLGVAIQKHLEMQFEQLQRAPASEDSLSVEGRRGPLRAVMQSLRRPSCCGCSGAAPE
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分子量
74.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GPRIN2, or G-protein Regulation and Interacting Protein 2, is a protein implicated in modulating various cellular processes, including signal transduction and cytoskeletal dynamics. Research into GPRIN2 has gained momentum due to its potential role in cellular signaling pathways, particularly those associated with G-protein-coupled receptors (GPCRs), which are crucial in numerous physiological responses and disease mechanisms. Abnormalities in GPRIN2 expression have been linked to various pathological conditions, including cancer and neurodegenerative diseases. The study of GPRIN2 recombinant proteins has provided valuable insights into its structural and functional characteristics, enabling scientists to explore its interactions with other cellular proteins and its regulatory functions. Advances in recombinant protein technology, such as the use of expression systems like E. coli and yeast, have facilitated the production of GPRIN2 for biochemical assays and structural studies. Understanding GPRIN2's role at the molecular level may reveal novel therapeutic targets for diseases where GPCR signaling is disrupted. Moreover, the elucidation of its interaction partners can provide a deeper understanding of the cellular signaling networks, enhancing our knowledge of both normal physiology and disease pathology. Thus, the ongoing research on GPRIN2 recombination proteins is critical for advancing our understanding of GPCR-related diseases and developing targeted interventions.
