Analytical Data
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Gene name
GPR61
- Application
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Alternative Names
GPR61; BALGR; GPCR3; G-protein coupled receptor 61; Biogenic amine receptor-like G-protein coupled receptor
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BZJ8
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Expression Region
1-451aa
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AA Sequence
MESSPIPQSSGNSSTLGRVPQTPGPSTASGVPEVGLRDVASESVALFFMLLLDLTAVAGNAAVMAVIAKTPALRKFVFVFHLCLVDLLAALTLMPLAMLSSSALFDHALFGEVACRLYLFLSVCFVSLAILSVSAINVERYYYVVHPMRYEVRMTLGLVASVLVGVWVKALAMASVPVLGRVSWEEGAPSVPPGCSLQWSHSAYCQLFVVVFAVLYFLLPLLLILVVYCSMFRVARVAAMQHGPLPTWMETPRQRSESLSSRSTMVTSSGAPQTTPHRTFGGGKAAVVLLAVGGQFLLCWLPYFSFHLYVALSAQPISTGQVESVVTWIGYFCFTSNPFFYGCLNRQIRGELSKQFVCFFKPAPEEELRLPSREGSIEENFLQFLQGTGCPSESWVSRPLPSPKQEPPAVDFRIPGQIAEETSEFLEQQLTSDIIMSDSYLRPAASPRLES
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Molecular Weight
49.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GPR61, an orphan G protein-coupled receptor (GPCR), has garnered attention in recent years due to its potential roles in various physiological processes and disease states. As a member of the class A GPCR family, GPR61 is characterized by its unique expression patterns in the brain and other tissues, suggesting involvement in neurotransmission and possibly other signaling pathways. Despite its discovery over two decades ago, the specific ligands and biological functions of GPR61 remain largely unidentified, making it a subject of intrigue in the field of molecular biology and pharmacology. Recent studies have indicated that GPR61 could be implicated in mood regulation, neuroprotection, and metabolic processes, highlighting the importance of elucidating its functional mechanisms. The development of recombinant GPR61 proteins facilitates the investigation of its structural characteristics and interactions with potential ligands, paving the way for therapeutic applications. Understanding GPR61's signaling pathways could also contribute to the broader comprehension of GPCRs and their roles in human health, potentially leading to novel strategies for treating psychiatric disorders, metabolic syndromes, and other related conditions. This highlights the significance of continued research on GPR61 as a promising target for drug discovery and therapeutic interventions.
