Analytical Data
-
基因名
GPR37L1
- Application
-
别名
GPR37L1; ETBRLP2; G-protein coupled receptor 37-like 1; Endothelin B receptor-like protein 2; ETBR-LP-2
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
O60883
-
表达区间
27-130aa
-
氨基酸序列
PLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQYVPEEWAEYPRPIHPAGLQPTKPLVATSPNPDKDGGTPDSGQELRGNLTGAPGQRLQIQNPLYPVTESSYSA
-
分子量
37.18 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GPR37L1, also known as the G protein-coupled receptor 37-like 1, is a member of the G protein-coupled receptor (GPCR) family that has garnered attention due to its potential roles in various physiological processes and pathological conditions. Research indicates that GPR37L1 may be involved in regulating neuronal signaling and has implications in neurodegenerative diseases, such as Parkinson's disease. The receptor is primarily expressed in the brain, suggesting its relevance in central nervous system functions. Additionally, its interaction with endogenous ligands, including prosaptide, has been implicated in neuroprotective effects and modulating synaptic activity. Given the rising interest in GPCRs as drug targets, the study of GPR37L1, specifically through the development of recombinant proteins, is crucial for elucidating its biological functions and signaling pathways. Understanding the molecular mechanisms underlying GPR37L1's action can aid in identifying new therapeutic strategies for neurodegenerative disorders and other related diseases. Therefore, the production and characterization of GPR37L1 recombinant proteins are essential for advancing our knowledge of this receptor's role in health and disease, making it a significant focus of ongoing research efforts.
