Analytical Data
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Gene name
GPR171
- Application
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Alternative Names
GPR171; H963; Probable G-protein coupled receptor 171; G-protein coupled receptor H963
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O14626
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Expression Region
1-319aa
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AA Sequence
MTNSSFFCPVYKDLEPFTYFFYLVFLVGIIGSCFATWAFIQKNTNHRCVSIYLINLLTAD FLLTLALPVKIVVDLGVAPWKLKIFHCQVTACLIYINMYLSIIFLAFVSIDRCLQLTHSC KIYRIQEPGFAKMISTVVWLMVLLIMVPNMMIPIKDIKEKSNVGCMEFKKEFGRNWHLLT NFICVAIFLNFSAIILISNCLVIRQLYRNKDNENYPNVKKALINILLVTTGYIICFVPYH IVRIPYTLSQTEVITDCSTRISLFKAKEATLLLAVSNLCFDPILYYHLSKAFRSKVTETF ASPKETKAQKEKLRCENNA
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Molecular Weight
36.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GPR171, a member of the G protein-coupled receptor (GPCR) family, has garnered significant interest due to its potential roles in various physiological processes and pathologies. Identified as a receptor for the neuropeptide SCFAs, GPR171 is implicated in the regulation of hunger, energy homeostasis, and potentially in neurological disorders. Research has shown that GPR171 is expressed in several tissues, including the brain, which has raised questions about its involvement in neuropsychiatric diseases such as depression and anxiety. The study of GPR171 recombinant protein is crucial for elucidating its structural and functional characteristics, which can provide insights into its signaling pathways and interactions with ligands. Moreover, developing GPR171-based therapeutic strategies could lead to novel treatments for metabolic and mental health disorders. Given the receptor's significance, creating a stable and functional recombinant protein is imperative for high-throughput screening, structural biology studies, and the development of specific inhibitors or modulators. This research ultimately aims to deepen the understanding of GPR171's role in health and disease, paving the way for innovative therapeutic interventions.
