Analytical Data
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Gene name
Fam111a
- Application
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Alternative Names
Fam111a；KIAA1895；Serine protease FAM111A
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96PZ2
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Expression Region
1-611aa
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AA Sequence
MSCKKQRSRKHSVNEKCNMKIEHYFSPVSKEQQNNCSTSLMRMESRGDPR ATTNTQAQRFHSPKKNPEDQTMPQNRTIYVTLKVNHRRNQDMKLKLTHSE NSSLYMALNTLQAVRKEIETHQGQEMLVRGTEGIKEYINLGMPLSCFPEG GQVVITFSQSKSKQKEDNHIFGRQDKASTECVKFYIHAIGIGKCKRRIVK CGKLHKKGRKLCVYAFKGETIKDALCKDGRFLSFLENDDWKLIENNDTIL ESTQPVDELEGRYFQVEVEKRMVPSAAASQNPESEKRNTCVLREQIVAQY PSLKRESEKIIENFKKKMKVKNGETLFELHRTTFGKVTKNSSSIKVVKLL VRLSDSVGYLFWDSATTGYATCFVFKGLFILTCRHVIDSIVGDGIEPSKW ATIIGQCVRVTFGYEELKDKETNYFFVEPWFEIHNEELDYAVLKLKENGQ QVPMELYNGITPVPLSGLIHIIGHPYGEKKQIDACAVIPQGQRAKKCQER VQSKKAESPEYVHMYTQRSFQKIVHNPDVITYDTEFFFGASGSPVFDSKG SLVAMHAAGFAYTYQNETRSIIEFGSTMESILLDIKQRHKPWYEEVFVNQ QDVEMMSDEDL
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Molecular Weight
70.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Fam111a is a gene that encodes a protein involved in various cellular processes, including DNA repair, cell cycle regulation, and response to stress. Recent studies have highlighted its crucial role in maintaining genomic stability and its potential implications in disease pathologies, particularly in cancer. The FAM111A protein is believed to participate in the formation of protein complexes at DNA damage sites, aiding in the recruitment of repair factors. This has led researchers to investigate the biochemical properties and functional mechanisms of Fam111a through the production of recombinant protein. By expressing and purifying Fam111a in various systems, scientists aim to elucidate its structure and interaction with other proteins. Such studies are essential for understanding its specific functions and regulatory pathways, as well as identifying potential therapeutic targets for diseases linked to FAM111A dysregulation. Ultimately, the exploration of Fam111a recombinant protein is paving the way for advancements in precision medicine and the development of innovative strategies to combat genetic disorders and malignancies.
