Analytical Data
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Gene name
Fam83d
- Application
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Alternative Names
Fam83d；C20orf129；Protein FAM83D
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Species
Mouse
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9D7I8
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Expression Region
1-585aa
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AA Sequence
MAARFELLDDLPAACLSPCGPPNPTELFSEARRLALEQLLAGGPDAWAAFLRRERLGRFLNADEVREVLGAAERPGEDGAAVAEDSFGSSHECSSGTYFPEQSDLEPPALELGWPSFYQGAYRGATRVEAHFQPRGAGAGGPYGCKDALRQQLRSAREVIAVVMDVFSDIDIFRDLQESCRKRGVAVYILLDQTLLPHFLDMCMDLRVHPEQEKLMTVRTITGNIYYARSGTKVVGKVHEKFTLIDGIRVATGSYSFTWTDGKLNSSNLVILSGQVVEHFDLEFRILYAQSEPISSKLLSNFQINSKFDHLADRKPQSKEPTLGNLLRMRLARLSSTPRKSNLGPEEPPKDRAKPKRPDSEASTISDEDYFHSHKDQLEDSKVADAATQTEPREEMAAVSLSEVGTQTSSSMMCVGTQTTVVTRAASSQATVWSKSTTTQTEADESFLPQGAQSKEGSPASKMSVSRSSSVRSSSSVSSQGSLASSVSSHVSLTAADLHTPAYPKYLGLGTPHLDLCLRDSFRNLSKERQVHFTGIRSRLTQMLTVLSRRTLFTEHYLSYSPGSFTRASTNLVSVRDIALYPPYQ
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Molecular Weight
66.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Fam83d, a member of the FAM83 family, has garnered considerable attention in the field of cancer research due to its potential role as an oncoprotein. Previous studies have implicated Fam83d in various cellular processes, including cell proliferation, differentiation, and apoptosis, making it a significant candidate for understanding tumorigenesis. Elevated levels of Fam83d have been observed in several types of cancers, correlating with poor prognosis and increased metastatic potential. The mechanisms by which Fam83d contributes to cancer progression are believed to involve the regulation of key signaling pathways, such as the RAS-MAPK pathway, which plays a pivotal role in cell growth and survival. Furthermore, Fam83d has been shown to interact with proteins that are crucial for cellular signaling and tumorigenic processes, suggesting that it may serve as a hub for oncogenic signaling. Investigating the structure and function of recombinant Fam83d protein can provide insights into its molecular mechanisms and interactions, paving the way for novel therapeutic strategies targeting its pathways. Overall, ongoing research into Fam83d is vital for elucidating its role in cancer biology and for developing effective interventions in tumor treatment.
