Cat: PA2000-8030

Recombinant Human GPM6B Protein,GST

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Analytical Data

  • Gene name

    GPM6B

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    GPM6B; M6B; Neuronal membrane glycoprotein M6-b; M6b

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q13491

  • Expression Region

    1-305aa

  • AA Sequence

    MKPAMETAAEENTEQSQERKVNSRAEMEIGRYHWMYPGSKNHQYHPVPTLGDRASPLSSPGCFECCIKCLGGVPYASLVATILCFSGVALFCGCGHVALAGTVAILEQHFSTNASDHALLSEVIQLMQYVIYGIASFFFLYGIILLAEGFYTTSAVKELHGEFKTTACGRCISGMFVFLTYVLGVAWLGVFGFSAVPVFMFYNIWSTCEVIKSPQTNGTTGVEQICVDIRQYGIIPWNAFPGKICGSALENICNTNEFYMSYHLFIVACAGAGATVIALLIYMMATTYNYAVLKFKSREDCCTKF

  • Molecular Weight

    59.9 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

GPM6B, a member of the glycoprotein M6 family, plays a crucial role in the development and functioning of the nervous system. It is a membrane protein that is predominantly expressed in neuronal tissues and is implicated in various physiological processes, including neuronal differentiation, synaptic plasticity, and cell signaling. Recent studies have highlighted GPM6B's involvement in neurodegenerative diseases, making it a potential biomarker and therapeutic target. Research has shown that GPM6B interacts with various signaling pathways, influencing cellular responses to external stimuli and contributing to the maintenance of neuronal integrity. Understanding the structure and function of GPM6B is essential for elucidating its role in health and disease. Scientists have turned to recombinant protein techniques to produce GPM6B in a controlled environment, facilitating advanced studies on its structure-function relationship and interactions with other cellular components. This research aims to unlock the mysteries of GPM6B’s biological functions and its potential therapeutic applications, particularly in the context of neurodegenerative conditions, where modulation of its activity could lead to innovative treatments.

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