Analytical Data
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基因名
ENTPD6
- Application
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别名
ENTPD6；CD39L2；IL6ST2;Ectonucleoside triphosphate diphosphohydrolase 6
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75354
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表达区间
61-484aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSKWHRATATQAFFSITRAAPGARWGQQA HSPLGTAADGHEVFYGIMFDAGSTGTRVHVFQFTRPPRETPTLTHETFKA LKPGLSAYADDVEKSAQGIRELLDVAKQDIPFDFWKATPLVLKATAGLRL LPGEKAQKLLQKVKEVFKASPFLVGDDCVSIMNGTDEGVSAWITINFLTG SLKTPGGSSVGMLDLGGGSTQIAFLPRVEGTLQASPPGYLTALRMFNRTY KLYSYSYLGLGLMSARLAILGGVEGQPAKDGKELVSPCLSPSFKGEWEHA EVTYRVSGQKAAASLHELCAARVSEVLQNRVHRTEEVKHVDFYAFSYYYD LAAGVGLIDAEKGGSLVVGDFEIAAKYVCRTLETQPQSSPFSCMDLTYVS LLLQEFGFPRSKVLKLTRKIDNVETSWALGAIFHYIDSLNRQKSPAS
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分子量
49 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ENTPD6, or ecto-nucleotide triphosphate diphosphohydrolase 6, is an enzyme belonging to the family of ecto-nucleotide triphosphate diphosphohydrolases that hydrolyzes nucleotide triphosphates and diphosphates on the extracellular surface of cells. Its study has garnered attention due to its potential roles in various physiological and pathological processes, including cell signaling, immune response, and modulation of the tumor microenvironment. Research has highlighted that ENTPD6 participates in the regulation of purinergic signaling, which is critical for cellular communication and has implications in diseases such as cancer, where altered nucleotide metabolism may affect tumor growth and immune evasion. Additionally, ENTPD6 is implicated in inflammatory conditions and has been identified as a potential therapeutic target. Understanding the biochemical properties and functions of ENTPD6, particularly through the development and characterization of recombinant protein, provides valuable insights into its mechanisms of action, potential inhibitors, and its role in disease pathology. This research not only enhances our understanding of purinergic signaling but also aims to explore the enzyme’s applicability in therapeutic contexts, offering new avenues for drug development and treatment strategies. The generation of recombinant ENTPD6 protein enables detailed studies on its enzymatic activity, substrate specificity, and interactions with other cellular components, paving the way for future investigations that could lead to novel therapeutic interventions.
