Analytical Data
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Gene name
SMOX
- Application
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Alternative Names
SMOX；C20orf16；SMO；Spermine oxidase
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NWM0
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Expression Region
1-555aa
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AA Sequence
MQSCESSGDS ADDPLSRGLR RRGQPRVVVI GAGLAGLAAA KALLEQGFTD VTVLEASSHI GGRVQSVKLG HATFELGATW IHGSHGNPIY HLAEANGLLE ETTDGERSVG RISLYSKNGV ACYLTNHGRR IPKDVVEEFS DLYNEVYNLT QEFFRHDKPV NAESQNSVGV FTREEVRNRI RNDPDDPEAT KRLKLAMIQQ YLKVESCESS SHSMDEVSLS AFGEWTEIPG AHHIIPSGFM RVVELLAEGI PAHVIQLGKP VRCIHWDQAS ARPRGPEIEP RGEGDHNHDT GEGGQGGEEP RGGRWDEDEQ WSVVVECEDC ELIPADHVIV TVSLGVLKRQ YTSFFRPGLP TEKVAAIHRL GIGTTDKIFL EFEEPFWGPE CNSLQFVWED EAESHTLTYP PELWYRKICG FDVLYPPERY GHVLSGWICG EEALVMEKCD DEAVAEICTE MLRQFTGNPN IPKPRRILRS AWGSNPYFRG SYSYTQVGSS GADVEKLAKP LPYTESSKTA PMQVLFSGEA THRKYYSTTH GALLSGQREA ARLIEMYRDL FQQGT
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Molecular Weight
61.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SMOX (spermine oxidase) is an enzyme that plays a crucial role in polyamine metabolism, particularly in the oxidative catabolism of spermine, a polyamine involved in cellular functions such as growth, differentiation, and apoptosis. Research on SMOX has gained attention in recent years due to its potential implications in various diseases, including cancer and neurodegenerative disorders. Elevated levels of SMOX have been linked to increased oxidative stress and cell death, suggesting that it could be a target for therapeutic interventions. Studies have focused on the structural and functional characterization of SMOX, as well as the development of recombinant forms of the protein to explore its enzymatic properties and regulatory mechanisms. Understanding the role of SMOX in cellular contexts could provide insights into its contribution to disease pathogenesis, paving the way for novel strategies in disease prevention and treatment. Furthermore, the use of recombinant SMOX in laboratory studies allows researchers to investigate its kinetic parameters and interactions with other cellular components, potentially uncovering new pathways involved in polyamine metabolism and their effects on cell physiology. Overall, the study of SMOX represents a promising area of research with significant implications for health and disease management.
