Analytical Data
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Gene name
Nr2c2
- Application
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Alternative Names
Nr2c2；TAK1；TR4；Nuclear receptor subfamily 2 group C member 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P49116
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Expression Region
3-592aa
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AA Sequence
SPSPRIQIISTDSAVASPQRIQIVTDQQTGQKIQIVTAVDASGSPKQQFILTSPDGAGTGKVILASPETSSAKQLIFTTSDNLVPGRIQIVTDSASVERLLGKTDVQRPQVVEYCVVCGDKASGRHYGAVSCEGCKGFFKRSVRKNLTYSCRSNQDCIINKHHRNRCQFCRLKKCLEMGMKMESVQSERKPFDVQREKPSNCAASTEKIYIRKDLRSPLIATPTFVADKDGARQTGLLDPGMLVNIQQPLIREDGTVLLATDSKAETSQGALGTLANVVTSLANLSESLNNGDTSEIQPEDQSASEITRAFDTLAKALNTTDSSSSPSLADGIDTSGGGSIHVISRDQSTPIIEVEGPLLSDTHVTFKLTMPSPMPEYLNVHYICESASRLLFLSMHWARSIPAFQALGQDCNTSLVRACWNELFTLGLAQCAQVMSLSTILAAIVNHLQNSIQEDKLSGDRIKQVMEHIWKLQEFCNSMAKLDIDGYEYAYLKAIVLFSPDHPGLTSTSQIEKFQEKAQMELQDYVQKTYSEDTYRLARILVRLPALRLMSSNITEELFFTGLIGNVSIDSIIPYILKMETAEYNGQIT
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Molecular Weight
68.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Nr2c2, also known as Nuclear Receptor Subfamily 2 Group C Member 2, is a member of the nuclear receptor superfamily, which plays a crucial role in various biological processes, including development, metabolism, and cellular differentiation. Research on Nr2c2 has gained significant attention due to its involvement in regulating gene expression and its potential implications in disease contexts, such as cancer and metabolic disorders. Nr2c2 acts as a transcription factor that modulates the expression of target genes in response to hormonal signals and other cellular cues. Its ability to dimerize with other nuclear receptors and its function in diverse tissues highlight its importance in maintaining cellular homeostasis. Moreover, understanding the signaling pathways and molecular mechanisms mediated by Nr2c2 can provide valuable insights into its role in health and disease. The study of recombinant Nr2c2 protein allows researchers to investigate its structure-function relationships and biochemical properties, further elucidating its biological functions. As interest in nuclear receptors continues to grow, Nr2c2 stands out as a promising target for therapeutic interventions and as a key player in the transcriptional networks governing physiological and pathological processes. Future research aims to uncover the detailed mechanisms by which Nr2c2 exerts its effects, paving the way for novel strategies to manipulate its activity in clinical settings.
