Cat: IPD-X41815

Recombinant Mouse Scamp4 Protein,His

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Analytical Data

  • Gene name

    Scamp4

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    (SC4)(Secretory carrier membrane protein 4)

  • Species

    Mouse

  • Source

    E. coli

  • Tag

    N- His

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9JKV5

  • Expression Region

    1-230aa

  • Molecular Weight

    26.9 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

Scamp4, a protein belonging to the secretory carrier membrane protein (SCAMP) family, plays a critical role in intracellular trafficking and membrane dynamics. This family, known for modulating membrane transport, has been linked to various cellular processes, including exocytosis, endocytosis, and synaptic function. Research into Scamp4 has gained momentum due to its unique expression pattern in neurons and its potential implications in neurobiology. Studies indicate that Scamp4 is involved in the regulation of synaptic vesicle cycles and neurotransmitter release, making it a candidate for understanding synaptic plasticity and communication between neurons. Furthermore, abnormalities in Scamp4 function may contribute to neurological disorders, thus attracting interest in therapeutic targets for conditions such as autism spectrum disorders and schizophrenia. Recent investigations employing advanced molecular biology techniques and imaging methods have begun to elucidate the mechanisms by which Scamp4 influences neuronal activity and synaptic efficiency, paving the way for future research aimed at translating these findings into clinical applications. Understanding Scamp4's role not only enhances our knowledge of neuronal function but also provides insights into the broader implications of membrane protein dynamics in health and disease.

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