Analytical Data
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基因名
DERA
- Application
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别名
DERA;Deoxyribose-phosphate aldolase
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y315
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表达区间
1-318aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMSAHNRGTELDLSWISKIQVNHPAVLRRAE QIQARRTVKKEWQAAWLLKAVTFIDLTTLSGDDTSSNIQRLCYKAKYPIR EDLLKALNMHDKGITTAAVCVYPARVCDAVKALKAAGCNIPVASVAAGFP AGQTHLKTRLEEIRLAVEDGATEIDVVINRSLVLTGQWEALYDEIRQFRK ACGEAHLKTILATGELGTLTNVYKASMIAMMAGSDFIKTSTGKETVNATF PVAIVMLRAIRDFFWKTGNKIGFKPAGGIRSAKDSLAWLSLVKEELGDEW LKPELFRIGASTLLSDIERQIYHHVTGRYAAYHDLPMS
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分子量
37 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DERA (deoxyribose-phosphate aldolase) is an enzyme that plays a crucial role in the salvage pathway of nucleotide synthesis, specifically in the conversion of ribose and deoxyribose sugars into nucleotide precursors. The research surrounding DERA recombinant proteins has gained significant attention due to their potential applications in biotechnology and medicine. Understanding the structure and function of DERA is essential for developing novel strategies to manipulate nucleotide metabolism in various organisms. Moreover, recombinant DERA proteins can be engineered for enhanced stability and activity, which can facilitate the production of nucleoside analogs important for antiviral and anticancer therapies. Studies have shown that recombinant DERA can be efficiently expressed in heterologous systems, allowing researchers to produce large quantities of the enzyme for biochemical assays and industrial applications. Additionally, structural studies have provided insights into the enzyme's catalytic mechanisms, further informing potential modifications for improved activity. As such, the ongoing research into DERA recombinant proteins represents a promising frontier in the fields of metabolic engineering, drug development, and synthetic biology.
