Analytical Data
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Gene name
DECR1
- Application
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Alternative Names
DECR1；DECR；SDR18C1;2.4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]. mitochondrial
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q16698
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Expression Region
35-335aa
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AA Sequence
MGSSHHHHHHSSGLVPRGSHM NTEALQSKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGA QCVIASRKMDVLKATAEQISSQTGNKVHAIQCDVRDPDMVQNTVSELIKV AGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFVTLEIGKQLI KAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMR FNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFL CSDYASWINGAVIKFDGGEEVLISGEFNDLRKVTKEQWDTIEELIRKTKG S
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Molecular Weight
34 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DECR1, or Decorin-Related Protein 1, is a member of the short-chain dehydrogenase/reductase (SDR) family, playing a crucial role in various biological processes, including lipid metabolism and oxidative stress responses. Its involvement in metabolic regulation has attracted attention in recent years, particularly in the context of metabolic disorders such as obesity, diabetes, and cardiovascular diseases. DECR1 functions as a key enzyme in the peroxisomal β-oxidation of fatty acids, contributing to the maintenance of cellular homeostasis and energy balance. Emerging studies suggest that DECR1 may affect mitochondrial function and reactive oxygen species (ROS) production, linking it to inflammation and cellular aging. Given these critical roles, researchers are increasingly focused on the molecular mechanisms underlying DECR1's biological functions, aiming to explore its potential as a therapeutic target for metabolic diseases. Understanding DECR1's structure, enzymatic activity, and regulatory pathways could provide deeper insights into metabolic health and disease mechanisms, making it a significant protein in both basic and applied biomedical research. The characterization of DECR1 recombinant proteins allows for the exploration of its enzymatic properties and interactions with other cellular components, paving the way for potential interventions in metabolic dysfunction and related disorders.
