Analytical Data
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Gene name
comC
- Application
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Alternative Names
(CSP)
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Species
Streptococcus mitis
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Source
E. coli
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Tag
N- His-KSI
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O33666
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Expression Region
25-40aa
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Molecular Weight
17.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The research on comC recombinant protein is rooted in the need to better understand the mechanisms of bacterial communication and its implications for pathogenesis. ComC, a key component of the competence signaling system in certain bacterial species, particularly in Streptococcus pneumoniae, plays a vital role in facilitating genetic transformation and intercellular communication. This protein is central to the competence pathway, where it acts as a signaling molecule that activates the expression of genes essential for DNA uptake and incorporation. Understanding the structure and function of comC is crucial for unraveling how bacteria coordinate group behavior and respond to environmental changes. Moreover, insights gained from studying comC could lead to novel therapeutic strategies targeting bacterial communication pathways, potentially mitigating issues like antibiotic resistance. As researchers employ techniques such as recombinant DNA technology and protein engineering, the exploration of comC promises to enhance our understanding of microbial dynamics in both health and disease contexts.
