Analytical Data
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基因名
P2RY14
- Application
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别名
P2RY14；GPR105；KIAA0001；P2Y purinoceptor 14
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15391
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表达区间
1-338aa
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氨基酸序列
MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL
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分子量
38.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
P2RY14, also known as the purinergic receptor P2Y14, is a G protein-coupled receptor that plays a vital role in mediating various physiological processes. It is primarily activated by UDP-glucose and is implicated in several biological functions, including immune responses, cell proliferation, and inflammation. Recent studies have highlighted the potential of P2RY14 as a therapeutic target in various diseases, such as cancer and autoimmune disorders. Given its regulatory role in the immune system, researchers are keen to understand how P2RY14 modulation can influence disease progression and treatment outcomes. The production of recombinant P2RY14 proteins enables detailed biochemical and biophysical studies, facilitating the exploration of its signaling pathways and interactions with potential ligands. By characterizing the receptor's structure and function, scientists aim to unveil its mechanisms of action, paving the way for the development of novel drugs that can selectively target this receptor. This research is particularly important as the therapeutic manipulation of P2RY14 could lead to new treatments that enhance immune function or mitigate unwanted inflammation, ultimately contributing to the advancement of precision medicine in the treatment of diverse health conditions.
