Analytical Data
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Gene name
UQCRFS1
- Application
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Alternative Names
UQCRFS1；Cytochrome b-c1 complex subunit Rieske. mitochondrial
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P47985
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Expression Region
79-274aa
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AA Sequence
SHTDIKVPDFSEYRRLEVLDSTKSSRESSEARKGFSYLVTGVTTVGVAYAAKNAVTQFVSSMSASADVLALAKIEIKLSDIPEGKNMAFKWRGKPLFVRHRTQKEIEQEAAVELSQLRDPQHDLDRVKKPEWVILIGVCTHLGCVPIANAGDFGGYYCPCHGSHYDASGRIRLGPAPLNLEVPTYEFTSDDMVIVG
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Molecular Weight
48.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
UQCRFS1, or Ubiquinone-Cytochrome c Reductase Fe-S Protein 1, plays a crucial role in the mitochondrial electron transport chain as part of complex III, which is essential for cellular respiration and energy production in eukaryotic cells. Research on UQCRFS1 has garnered interest due to its implications in various biological processes and potential links to metabolic disorders and neurodegenerative diseases. Understanding the structural and functional characteristics of recombinantly expressed UQCRFS1 can provide insights into its mechanistic role in electron transfer and its interactions with other mitochondrial components. Furthermore, the recombinant protein can serve as a valuable tool for exploring the functional consequences of genetic mutations, elucidating the fundamental pathways of oxidative phosphorylation, and developing therapeutic strategies for diseases associated with mitochondrial dysfunction. Investigating UQCRFS1 at a molecular level opens avenues for innovative approaches in drug development and personalized medicine, highlighting its significance in both basic and applied biological research.
