Analytical Data
-
基因名
CTTN
- Application
-
别名
CTTN；EMS1；Src substrate cortactin
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q14247
-
表达区间
1-513aa
-
氨基酸序列
MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQ EHINIHKLRENVFQEHQTLKEKELETGPKASHGYGGKFGVEQDRMDKSAV GHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHAS QKDYSSGFGGKYGVQADRVDKSAVGFDYQGKTEKHESQRDYSKGFGGKYG IDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGW DHQEKLQLHESQKDYSKGFGGKYGVQKDRMDKNASTFEDVTQVSSAYQKT VPVEAVTSKTSNIRANFENLAKEKEQEDRRKAEAERAQRMAKERQEQEEA RRKLEEQARAKTQTPPVSPAPQPTEERLPSSPVYEDAASFKAELSYRGPV SGTEPEPVYSMEAADYREASSQQGLAYATEAVYESAEAPGHYPAEDSTYD EYENDLGITAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGR YGLFPANYVELRQ
-
分子量
84 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CTTN (Cortactin) is an actin-bindin g protein that plays a crucial role in actin cytoskeleton dynamics, cell migration, and adhesion. It has been implicated in various cellular processes, including endocytosis, cell signaling, and the formation of membrane protrusions. Research has shown that abnormal expression and activity of CTTN are associated with several diseases, particularly cancer, where it contributes to increased cell motility and invasion. Given its significant role in cancer progression, CTTN has emerged as a potential therapeutic target. Understanding the structure and function of CTTN is vital for developing effective strategies to modulate its activity in pathological conditions. The recombinant production of CTTN provides a valuable tool for studying its biochemical properties, interaction with other proteins, and its role in cellular processes. This research not only enhances our understanding of CTTN’s contribution to cellular mechanics but also aids in the identification of novel drug targets and therapeutic approaches in cancer treatment. Overall, the study of CTTN recombinant proteins is essential for deciphering the complex mechanisms governing cell behavior and developing innovative strategies to counteract diseases associated with its dysregulation.
