Analytical Data
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基因名
SYNCRIP
- Application
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别名
SYNCRIP；HNRPQ；NSAP1；Heterogeneous nuclear ribonucleoProtein Q
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O60506
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表达区间
2-191aa
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氨基酸序列
ATEHVNGNGTEEPMDTTSAVIHSENFQTLLDAGLPQKVAEKLDEIYVAGLVAHSDLDERAIEALKEFNEDGALAVLQQFKDSDLSHVQNKSAFLCGVMKTYRQREKQGTKVADSSKGPDEAKIKALLERTGYTLDVTTGQRKYGGPPPDSVYSGQQPSVGTEIFVGKIPRDLFEDELVPLFEKAGPIWDL
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分子量
47.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SYNCRIP (Synaptic Cellular RNA Binding Protein) is a crucial RNA-binding protein that plays a significant role in post-transcriptional regulation of gene expression. Its involvement in neuronal development and synaptic function has garnered attention in recent years, particularly due to its implications in neurological disorders. Research indicates that SYNCRIP is essential for mRNA localization, stability, and translation, making it a key player in the regulation of synaptic proteins. Additionally, evidence suggests that it may interact with several RNA elements and partner proteins to modulate neuronal activity and plasticity. Given the importance of synaptic transmission in cognitive processes, understanding the mechanisms of SYNCRIP can provide vital insights into the molecular underpinnings of learning and memory. Furthermore, dysregulation of SYNCRIP has been associated with various neurodegenerative diseases, adding a layer of complexity and urgency to its study. The exploration of SYNCRIP not only enhances our understanding of molecular biology in the nervous system but also holds potential for identifying therapeutic targets for conditions linked to synaptic dysfunction. Thus, ongoing research into the functions and interactions of SYNCRIP is essential for advancing our knowledge of fundamental neurological processes and developing new interventions for brain-related disorders.
