Analytical Data
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基因名
PITPNM1
- Application
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别名
PITPNM1;DRES9;NIR2;PITPNM;Membrane-associated phosphatidylinositol transfer Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O00562
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表达区间
1-238aa
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氨基酸序列
MLIKEYHILLPMSLDEYQVAQLYMIQKKSREESSGEGSGVEILANRPYTDGPGGSGQYTHKVYHVGSHIPGWFRALLPKAALQVEEESWNAYPYTRTRYTCPFVEKFSIEIETYYLPDGGQQPNVFNLSGAERRQRILDTIDIVRDAVAPGEYKAEEDPRLYHSVKTGRGPLSDDWARTAAQTGPLMCAYKLCKVEFRYWGMQAKIEQFIHDVGLRRVMLRAHRQAWCWQDEWTELSM
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分子量
54.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PITPNM1 (phosphatidylinositol transfer protein, membrane-associated 1) is a crucial protein involved in cellular lipid metabolism and signaling pathways. It plays a vital role in the transport of phosphoinositides between membrane compartments, which is essential for various cellular processes, including endocytosis, exocytosis, and signal transduction. Recent research has emphasized the significance of PITPNM1 in maintaining the integrity of cellular membranes and its potential implications in diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. Recombinant PITPNM1 protein studies have gained attention as they provide insights into its structural and functional characteristics, enabling a deeper understanding of lipid homeostasis and membrane dynamics. By utilizing purification techniques and advanced analytical methods, researchers aim to elucidate the mechanistic details of PITPNM1's role in cellular functions and its interaction with other proteins and lipids. These studies pave the way for novel therapeutic strategies that target PITPNM1-related pathways, highlighting its potential as a biomarker or therapeutic target in disease contexts. Understanding the intricate functions of PITPNM1 through recombinant protein research is essential for uncovering new avenues in cell biology and medicine.












