Analytical Data
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基因名
SLC39A6
- Application
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别名
SLC39A6；LIV1；ZIP6；Zinc transporter ZIP6
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q13433
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表达区间
29-325aa
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氨基酸序列
FPQTTEKISPNWESGINVDLAISTRQYHLQQLFYRYGENNSLSVEGFRKLLQNIGIDKIKRIHIHHDHDHHSDHEHHSDHERHSDHEHHSEHEHHSDHDHHSHHNHAASGKNKRKALCPDHDSDSSGKDPRNSQGKGAHRPEHASGRRNVKDSVSASEVTSTVYNTVSEGTHFLETIETPRPGKLFPKDVSSSTPPSVTSKSRVSRLAGRKTNESVSEPRKGFMYSRNTNENPQECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAW
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分子量
35.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLC39A6, also known as ZIP6, is a member of the SLC39 family of solute carriers that plays a crucial role in zinc homeostasis. Zinc is an essential trace element that is vital for numerous biological processes, including enzyme activity, DNA synthesis, and cell division. Dysregulation of zinc transport can lead to various health issues, including developmental disorders, immune dysfunction, and neurodegenerative diseases. Research on the recombinant protein of SLC39A6 has gained attention due to its potential implications in understanding zinc metabolism and its role in disease mechanisms. SLC39A6 is primarily located in the plasma membrane and is responsible for the influx of zinc ions into cells, thereby influencing cellular zinc levels and physiological functions. Characterizing the recombinant SLC39A6 protein can help elucidate its structure-function relationships, regulatory mechanisms, and interaction with other metal transporters. Additionally, studies involving the recombinant form of this protein can provide insights into the impact of specific mutations or polymorphisms associated with disorders linked to zinc deficiency or overload. Given the critical role of zinc in health, understanding SLC39A6's functionality may contribute to developing therapeutic strategies for zinc-related diseases, enhancing our knowledge of metal ion transport, and potentially paving the way for novel interventions targeting zinc homeostasis.
