Analytical Data
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Gene name
SLC39A6
- Application
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Alternative Names
SLC39A6；LIV1；ZIP6；Zinc transporter ZIP6
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13433
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Expression Region
29-325aa
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AA Sequence
FPQTTEKISPNWESGINVDLAISTRQYHLQQLFYRYGENNSLSVEGFRKLLQNIGIDKIKRIHIHHDHDHHSDHEHHSDHERHSDHEHHSEHEHHSDHDHHSHHNHAASGKNKRKALCPDHDSDSSGKDPRNSQGKGAHRPEHASGRRNVKDSVSASEVTSTVYNTVSEGTHFLETIETPRPGKLFPKDVSSSTPPSVTSKSRVSRLAGRKTNESVSEPRKGFMYSRNTNENPQECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAW
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Molecular Weight
35.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SLC39A6, also known as ZIP6, is a member of the SLC39 family of solute carriers that plays a crucial role in zinc homeostasis. Zinc is an essential trace element that is vital for numerous biological processes, including enzyme activity, DNA synthesis, and cell division. Dysregulation of zinc transport can lead to various health issues, including developmental disorders, immune dysfunction, and neurodegenerative diseases. Research on the recombinant protein of SLC39A6 has gained attention due to its potential implications in understanding zinc metabolism and its role in disease mechanisms. SLC39A6 is primarily located in the plasma membrane and is responsible for the influx of zinc ions into cells, thereby influencing cellular zinc levels and physiological functions. Characterizing the recombinant SLC39A6 protein can help elucidate its structure-function relationships, regulatory mechanisms, and interaction with other metal transporters. Additionally, studies involving the recombinant form of this protein can provide insights into the impact of specific mutations or polymorphisms associated with disorders linked to zinc deficiency or overload. Given the critical role of zinc in health, understanding SLC39A6's functionality may contribute to developing therapeutic strategies for zinc-related diseases, enhancing our knowledge of metal ion transport, and potentially paving the way for novel interventions targeting zinc homeostasis.
