Analytical Data
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基因名
SLC30A7
- Application
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别名
SLC30A7;ZNT7;ZNTL2;Zinc transporter 7
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NEW0
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表达区间
1-376aa
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氨基酸序列
MLPLSIKDDEYKPPKFNLFGKISGWFRSILSDKTSRNLFFFLCLNLSFAFVELLYGIWSNCLGLISDSFHMFFDSTAILAGLAASVISKWRDNDAFSYGYVRAEVLAGFVNGLFLIFTAFFIFSEGVERALAPPDVHHERLLLVSILGFVVNLIGIFVFKHGGHGHSHGSGHGHSHSLFNGALDQAHGHVDHCHSHEVKHGAAHSHDHAHGHGHFHSHDGPSLKETTGPSRQILQGVFLHILADTLGSIGVIASAIMMQNFGLMIADPICSILIAILIVVSVIPLLRESVGILMQRTPPLLENSLPQCYQRVQQLQGVYSLQEQHFWTLCSDVYVGTLKLIVAPDADARWILSQTHNIFTQAGVRQLYVQIDFAAM
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分子量
41.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLC30A7, a member of the solute carrier family, encodes a protein responsible for the transport of zinc ions across cellular membranes. Zinc plays a crucial role in various biological processes, including enzyme activity, gene expression, and cellular signaling. Dysregulation of zinc homeostasis has been implicated in a myriad of health issues, such as metabolic disorders, neurodegenerative diseases, and immune dysfunctions. Research on SLC30A7 has gained attention due to its association with disorders like diabetes and obesity, where zinc transport may impact insulin signaling and glucose metabolism. Understanding the structure and function of SLC30A7 through recombinant protein studies provides insights into its role in cellular zinc transport mechanisms and its potential as a therapeutic target. The production of recombinant SLC30A7 protein allows for detailed biochemical and biophysical analyses, facilitating the exploration of its functional properties and interactions with other cellular components. This line of research not only aids in elucidating fundamental mechanisms of zinc homeostasis but also paves the way for developing novel strategies to address diseases linked to SLC30A7 malfunction.












