Analytical Data
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Gene name
DUSP26
- Application
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Alternative Names
Dual specificity phosphatase SKRP3Low-molecular-mass dual-specificity phosphatase 4 ;DSP-4 ;LDP-4Mitogen-activated protein kinase phosphatase 8 ;MAP kinase phosphatase 8 ;MKP-8Novel amplified gene in thyroid anaplastic cancer
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Species
Human
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BV47
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Expression Region
1-211aa
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Molecular Weight
39.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DUSP26, a member of the dual-specificity phosphatase (DUSP) family, plays a significant role in cellular signaling by regulating mitogen-activated protein (MAP) kinase pathways. Researchers have identified DUSP26 as a negative regulator of MAP kinases, which are crucial for various cellular processes, including proliferation, differentiation, and stress responses. The importance of DUSP26 is underscored by its involvement in immune responses and potential implications in cancer biology, where altered expression can lead to dysregulated signaling cascades. The study of DUSP26 recombinant protein facilitates a deeper understanding of its biochemical characteristics, interaction with MAP kinases, and its impact on cellular functions. Moreover, investigating the post-translational modifications and regulatory mechanisms governing DUSP26 activity can reveal therapeutic targets for diseases associated with MAP kinase dysregulation. This makes DUSP26 a promising candidate for further research in the fields of molecular biology and drug development.
