Analytical Data
-
Gene name
S1pr2
- Application
-
Alternative Names
(S1P receptor 2)(S1P2)(AGR16)(Endothelial differentiation G-protein coupled receptor 5)(G-protein coupled receptor H218)(Sphingosine 1-phosphate receptor Edg-5)(S1P receptor Edg-5)
-
Species
Rat
-
Source
E. coli
-
Tag
C- His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P47752
-
Expression Region
1-352aa
-
Molecular Weight
41.6 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
S1PR2, or sphingosine-1-phosphate receptor 2, is a member of the sphingosine-1-phosphate receptor family, which plays a critical role in various physiological and pathological processes, including immune response, cardiovascular function, and cell migration. The receptor is primarily involved in mediating the effects of sphingosine-1-phosphate (S1P), a bioactive lipid that functions as a signaling molecule influencing cellular behavior. Research has highlighted the importance of S1PR2 in regulating lymphocyte migration, vascular permeability, and the modulation of inflammation, making it a potential therapeutic target for diseases such as cancer, autoimmune disorders, and cardiovascular diseases.
Furthermore, S1PR2 has been implicated in the development and progression of several types of cancer, where its signaling pathways can influence tumor growth and metastasis. The ability to manipulate S1PR2 expression and activity presents opportunities for developing novel treatment strategies. Given its significant roles in both health and disease, the recombinant expression of S1PR2 has become a focus of research. Understanding the structure and function of recombinant S1PR2 can provide insights into its mechanism of action, facilitate drug design, and improve therapeutic efficacy. The production of high-quality S1PR2 recombinant protein is essential for biochemical assays, structural studies, and the development of S1P-based therapeutics, thus highlighting the relevance of S1PR2 in current biomedical research.
