Analytical Data
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基因名
XCR1
- Application
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别名
XCR1；CCXCR1；GPR5；Chemokine XC receptor 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P46094
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表达区间
1-333aa
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氨基酸序列
MESSGNPESTTFFYYDLQSQPCENQAWVFATLATTVLYCLVFLLSLVGNSLVLWVLVKYESLESLTNIFILNLCLSDLVFACLLPVWISPYHWGWVLGDFLCKLLNMIFSISLYSSIFFLTIMTIHRYLSVVSPLSTLRVPTLRCRVLVTMAVWVASILSSILDTIFHKVLSSGCDYSELTWYLTSVYQHNLFFLLSLGIILFCYVEILRTLFRSRSKRRHRTVKLIFAIVVAYFLSWGPYNFTLFLQTLFRTQIIRSCEAKQQLEYALLICRNLAFSHCCFNPVLYVFVGVKFRTHLKHVLRQFWFCRLQAPSPASIPHSPGAFAYEGASFY
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分子量
38.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
XCR1 (C-X-C motif chemokine receptor 1) is a chemokine receptor that plays a crucial role in immune response regulation and dendritic cell migration. It is primarily expressed on a subset of dendritic cells, particularly those involved in the activation of T cells and the modulation of adaptive immunity. Researchers have increasingly focused on XCR1 due to its significant role in maintaining immune homeostasis and its potential implications in various diseases, including autoimmune disorders, infections, and cancer. The study of XCR1 recombinant protein has been pivotal for understanding its function at a molecular level, allowing scientists to explore its interactions with various ligands and downstream signaling pathways. Recombination technology enables the production of this protein in a laboratory setting, providing a valuable tool for investigating the receptor’s pharmacological properties, therapeutic potentials, and its role in immune system dynamics. Additionally, the ability to produce XCR1 in recombinant form facilitates the development of novel targeted therapies that could manipulate the immune response, ultimately aiding in the treatment of diseases characterized by dysregulated immune functions. As such, XCR1 recombinant protein research is a promising avenue for advancing our understanding of immune mechanisms and for developing innovative therapeutic strategies.
