Cat: IPD-X41676

Recombinant Human ENAM Protein (Baculovirus),His

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Analytical Data

  • Gene name

    ENAM

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Species

    Human

  • Source

    Baculovirus

  • Tag

    C- His

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9NRM1

  • Expression Region

    1043-1142aa

  • Molecular Weight

    12.4 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

ENAM, or Enamelin, is a crucial protein involved in the formation of tooth enamel, the hardest substance in the human body. Its significance lies in its role during the enamel maturation stage, where it contributes to the mineralization and structural integrity of enamel crystals. Research into ENAM has gained traction due to its implications in dental health and genetic studies. Mutations in the ENAM gene have been linked to various enamel hypoplasia conditions, resulting in weakened enamel and increased susceptibility to dental caries. Furthermore, ENAM serves as a potential biomarker for evaluating enamel development and density. Advances in genetic analysis and molecular biology techniques have paved the way for a deeper understanding of ENAM's function and regulatory mechanisms. This research not only enhances our comprehension of tooth development but also opens avenues for therapeutic interventions in enamel-related disorders. Understanding the molecular pathways involving ENAM could lead to innovative treatments aimed at preventing enamel defects and improving oral health outcomes. Overall, the study of ENAM is vital not only for its biological significance but also for its potential impact on dentistry and genetic counseling.

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