Analytical Data
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Gene name
ARPC5L
- Application
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Alternative Names
Arp2/3 complex 16KDA subunit
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O15511
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Expression Region
1-154aa
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Molecular Weight
43.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ARPC5L, also known as Actin Related Protein 2/3 Complex Subunit 5-Like, is a gene that encodes a protein involved in the regulation of actin dynamics, which is critical for various cellular processes such as cell motility, division, and structure maintenance. Research on ARPC5L has gained attention due to its potential role in the pathophysiology of several diseases, including cancer and neurological disorders. The protein is a part of the ARP2/3 complex, which is instrumental in the nucleation of new actin filaments and the formation of branched actin networks, pivotal for cellular architecture and movement. Understanding the function and interactions of ARPC5L through recombinant protein studies can provide insights into its mechanisms and contributions to cellular functions. Additionally, examining its expression patterns and mutations may reveal its involvement in disease states, making it a promising target for therapeutic intervention. Current studies focus on the structural biology of ARPC5L to develop inhibitors or modulators that could alter its activity, thereby providing new strategies for treating diseases linked to dysregulated actin dynamics. Overall, the research of ARPC5L recombinant proteins is crucial for elucidating its biological functions and therapeutic potential, making it a significant area of study in cellular biology and medicine.
