Analytical Data
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基因名
CCR1
- Application
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别名
CCR1；CMKBR1；CMKR1；SCYAR1；C-C chemokine receptor type 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P32246
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表达区间
1-355aa
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氨基酸序列
METPNTTEDYDTTTEFDYGDATPCQKVNERAFGAQLLPPLYSLVFVIGLVGNILVVLVLVQYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDYKLKDDWVFGDAMCKILSGFYYTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALAILASMPGLYFSKTQWEFTHHTCSLHFPHESLREWKLFQALKLNLFGLVLPLLVMIICYTGIIKILLRRPNEKKSKAVRLIFVIMIIFFLFWTPYNLTILISVFQDFLFTHECEQSRHLDLAVQVTEVIAYTHCCVNPVIYAFVGERFRKYLRQLFHRRVAVHLVKWLPFLSVDRLERVSSTSPSTGEHELSAGF
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分子量
42.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCR1 (C-C chemokine receptor type 1) is a member of the chemokine receptor family, primarily involved in the immune system's response to inflammation and infection. It plays a crucial role in the recruitment of immune cells, such as monocytes and T lymphocytes, to sites of injury or infection, thereby mediating various physiological and pathological processes. The study of CCR1 has gained significant attention due to its association with several diseases, including autoimmune disorders, viral infections, and cancer. Researchers have focused on understanding the receptor's structure, function, and signaling pathways to develop therapeutic strategies targeting CCR1. In particular, recombinant protein technologies have enabled the production of CCR1 for various applications, including the development of monoclonal antibodies and small-molecule inhibitors. By elucidating the receptor's role in immune responses and its potential as a therapeutic target, CCR1 research holds promise for advancing treatments in inflammatory diseases and improving patient outcomes.
