Analytical Data
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Gene name
CNN2
- Application
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Alternative Names
CNN2;Calponin-2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q99439
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Expression Region
1-131aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMSSTQFN KGPSYGLSAE VKNRLLSKYD PQKEAELRTW IEGLTGLSIG PDFQKGLKDG TILCTLMNKL QPGSVPKINR SMQNWHQLEN LSNFIKAMVS YGMNPVDLFE ANDLFESGNM TQVQVSLLAL AGKA
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Molecular Weight
17 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of CNN2 recombinant protein is rooted in the exploration of the cell cycle and its regulation, particularly in relation to cancer biology. CNN2, or calponin 2, is part of the calponin family of proteins, which are known to play significant roles in the organization of the cytoskeleton and the regulation of smooth muscle contraction. As a regulator of actin dynamics, CNN2 is implicated in various cellular processes, including cell migration, proliferation, and differentiation. Abnormal expression or function of CNN2 has been associated with several diseases, especially cancer, where altered signaling pathways can lead to enhanced tumor invasiveness and metastasis. Consequently, understanding the expression patterns, structure, and function of CNN2 as a recombinant protein can offer insights into its potential role as a biomarker or therapeutic target. The production and characterization of CNN2 recombinant protein enable researchers to study its interactions with other cellular components and to elucidate its implications in health and disease. This research is critical for developing new strategies in cancer treatment and understanding the underlying mechanisms of cell biology.
