Analytical Data
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Gene name
SNX16
- Application
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Species
Human
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P57768
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Expression Region
1-344aa
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Molecular Weight
43.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SNX16, a member of the sorting nexin family, plays a critical role in intracellular trafficking and membrane dynamics. Its involvement in endosomal sorting processes has garnered attention in recent years, particularly due to its potential implications in various cellular mechanisms and disease states. The protein is known for its distinct phosphoinositide-binding domain, which allows it to interact with membrane-bound phospholipids, facilitating the recruitment of other proteins to specific endosomal compartments. Research into SNX16 has suggested its participation in processes such as receptor recycling, autophagy, and the sorting of ubiquitinated cargo, highlighting its importance in maintaining cellular homeostasis. Given the growing interest in understanding the molecular basis of cellular dysfunction in diseases, including cancer and neurodegenerative disorders, the study of SNX16 as a recombinant protein offers a valuable opportunity to elucidate its biochemical properties and functional roles. Advances in recombinant protein technology allow for the expression and purification of SNX16, enabling detailed biochemical assays and structural studies. By dissecting its mechanisms of action, researchers aim to uncover potential therapeutic targets and develop strategies to modulate SNX16 activity, ultimately contributing to the broader understanding of cellular regulation and pathogenesis. The continued exploration of SNX16 not only enhances our fundamental knowledge of membrane trafficking but also paves the way for novel biomedical applications.
