Analytical Data
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Gene name
CNDP2
- Application
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Alternative Names
CNDP2；CN2；CPGL；HEL-S-13;Cytosolic non-specific dipeptidase
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96KP4
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Expression Region
1-475aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMAALTTL FKYIDENQDR YIKKLAKWVA IQSVSAWPEK RGEIRRMMEV AAADVKQLGG SVELVDIGKQ KLPDGSEIPL PPILLGRLGS DPQKKTVCIY GHLDVQPAAL EDGWDSEPFT LVERDGKLYG RGSTDDKGPV AGWINALEAY QKTGQEIPVN VRFCLEGMEE SGSEGLDELI FARKDTFFKD VDYVCISDNY WLGKKKPCIT YGLRGICYFF IEVECSNKDL HSGVYGGSVH EAMTDLILLM GSLVDKRGNI LIPGINEAVA AVTEEEHKLY DDIDFDIEEF AKDVGAQILL HSHKKDILMH RWRYPSLSLH GIEGAFSGSG AKTVIPRKVV GKFSIRLVPN MTPEVVGEQV TSYLTKKFAE LRSPNEFKVY MGHGGKPWVS DFSHPHYLAG RRAMKTVFGV EPDLTREGGS IPVTLTFQEA TGKNVMLLPV GSADDGAHSQ NEKLNRYNYI EGTKMLAAYL YEVSQLKD
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Molecular Weight
55 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of CNDP2 recombinant protein is rooted in the exploration of its potential implications in various biological processes and diseases. CNDP2, also known as "carnosine dipeptidase 2," is an enzyme that plays a crucial role in the metabolism of bioactive peptides, particularly in the breakdown of carnosine, a dipeptide involved in cellular functions such as antioxidant defense, pH buffering, and modulation of intracellular calcium levels. Elevated levels of CNDP2 have been linked to various pathophysiological conditions, including diabetes and neurodegenerative diseases, highlighting its significance as a therapeutic target. The production of recombinant CNDP2 facilitates detailed biochemical and structural characterizations, enabling researchers to investigate its enzymatic activity, substrate specificity, and regulatory mechanisms. Furthermore, understanding the structure-function relationship of CNDP2 can lead to the development of potent inhibitors or modulators that may serve as novel therapeutic agents. The recombinant protein is also essential for exploring its role in physiological contexts, including muscle metabolism and brain function. Thus, researching CNDP2 recombinant protein not only enhances our understanding of fundamental biological processes but also paves the way for potential therapeutic advancements in treating related health issues.
