Analytical Data
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基因名
CHCHD4
- Application
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别名
Coiled-coil-helix-coiled-coil-helix domain-containing protein 4
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种属
Human
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N4Q1
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表达区间
1-142aa
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分子量
32 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CHCHD4, a member of the conserved mitochondrial protein family, has gained considerable attention in recent years due to its critical role in mitochondrial function and cellular metabolism. This protein is known to be involved in the regulation of oxidative phosphorylation and mitochondrial dynamics, influencing energy production in cells. Disruptions in CHCHD4 function have been linked to various diseases, including neurodegenerative disorders and cancer, highlighting its potential as a therapeutic target. Researchers are increasingly focused on the recombinant expression of CHCHD4 to study its biochemical properties, interaction with other mitochondrial proteins, and its influence on cellular stress responses. The production of recombinant CHCHD4 allows for detailed structural and functional analyses, paving the way for understanding the mechanisms underlying its role in mitochondria. As studies progress, insights into CHCHD4 may reveal novel approaches for treating mitochondrial dysfunction-related diseases, making it a promising candidate for further exploration in both basic and applied research contexts. The ongoing investigation into CHCHD4's functionalities and implications in health and disease is essential for the development of targeted therapies, thus emphasizing the relevance of recombinant protein technology in advancing our knowledge of mitochondrial biology.












