Analytical Data
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基因名
NPHN
- Application
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别名
NPHN；NPHN；Nephrin
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O60500
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表达区间
33-122aa
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氨基酸序列
GFWALPENLTVVEGASVELRCGVSTPGSAVQWAKDGLLLGPDPRIPGFPR YRLEGDPARGEFHLHIEACDLSDDAEYECQVGRSEMGPEL
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分子量
36 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NPHN (Nuclear Pore Complex Protein) recombinant protein research has gained significant interest due to its critical role in cellular functions, particularly in nucleocytoplasmic transport, which is essential for maintaining cellular homeostasis and regulating gene expression. The Nuclear Pore Complex (NPC) is a large protein assembly that spans the nuclear envelope, facilitating the selective transport of proteins and RNA molecules between the nucleus and cytoplasm. Abnormalities in NPHN proteins have been implicated in various diseases, including cancer and neurodegenerative disorders, highlighting their importance in health and disease. Recent advancements in recombinant DNA technology and protein expression systems have enabled the production of NPHN proteins, which provide valuable tools for studying their structure, function, and interactions within the NPC. Additionally, the ability to produce these proteins in a high-purity form allows researchers to explore their potential as therapeutic targets or biomarkers. Understanding the mechanistic roles of NPHN proteins may lead to new insights into the development of diagnostic and treatment strategies for NPC-related diseases, ultimately contributing to improved healthcare outcomes.
