Analytical Data
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基因名
AQP1
- Application
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别名
AQP1;CHIP28;Aquaporin-1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P29972
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表达区间
2-269aa
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氨基酸序列
ASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYDLDADDINSRVEMKPK
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分子量
41.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
AQP1 (Aquaporin 1) is a member of the aquaporin family of transmembrane water channel proteins, initially discovered in the early 1990s. It is primarily expressed in the kidneys, eyes, and blood-brain barrier, playing a crucial role in regulating water homeostasis by facilitating the transport of water molecules across cell membranes. Due to its integral function in physiological processes such as urine concentration, lens transparency, and brain fluid homeostasis, AQP1 has garnered significant interest in various fields, including physiology, medicine, and biotechnology. Research on recombinant AQP1 protein is aimed at elucidating its structure-function relationships, understanding its role in diseases such as edema, glaucoma, and cancer, and exploring its potential as a therapeutic target. The production of AQP1 as a recombinant protein allows for detailed biochemical characterization, functional assays, and structure determination, enabling researchers to investigate how specific mutations or modifications could affect its activity. Additionally, recombinant AQP1 is utilized in drug delivery systems and bioengineering applications, highlighting its importance in both basic and applied research. The ongoing exploration of AQP1 not only enhances our knowledge of cellular water transport mechanisms but also opens up new avenues for developing therapies targeting water balance disorders.












