Analytical Data
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基因名
CCL19
- Application
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别名
CCL19;ELC;MIP3B;SCYA19;C-C motif chemokine 19
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q99731
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表达区间
22-98aa
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氨基酸序列
GTNDAEDCCLSVTQKPIPGYIVRNFHYLLIKDGCRVPAVVFTTLRGRQLCAPPDQPWVERIIQRLQRTSAKMKRRSS
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分子量
35.8kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCL19, also known as chemokine (C-C motif) ligand 19, is a crucial member of the chemokine family that plays a significant role in immune system regulation, particularly in lymphocyte migration and tissue homing. It primarily acts by binding to its receptor, CCR7, which is essential for the trafficking of T cells and dendritic cells to lymphoid organs and inflammatory sites. Due to its pivotal role in immune responses, CCL19 has garnered attention in various fields, including immunology, oncology, and infectious diseases. In cancer research, manipulating CCL19 signaling pathways is being explored as a strategy for enhancing anti-tumor immunity and developing novel immunotherapies. Moreover, the recombinant production of CCL19 protein has facilitated its study in vitro and in vivo, allowing researchers to better understand its biological functions, receptor interactions, and potential therapeutic applications. By examining the effects of CCL19 on immune cells, scientists aim to elucidate its mechanisms of action, paving the way for innovative treatments for conditions such as cancer, autoimmunity, and chronic inflammation. The ongoing exploration of CCL19 and its recombinant protein forms continues to unveil its complexities, contributing significantly to our understanding of the immune landscape and presenting new avenues for therapeutic interventions.












