Analytical Data
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基因名
CCL15
- Application
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别名
CCL15;MIP5;NCC3;SCYA15;C-C motif chemokine 15
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q16663
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表达区间
46-113aa
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氨基酸序列
SFHFAADCCT SYISQSIPCS LMKSYFETSS ECSKPGVIFL TKKGRQVCAK PSGPGVQDCM KKLKPYSI
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分子量
7.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCL15, also known as macrophage inflammatory protein-1 gamma (MIP-1γ), is a chemokine belonging to the CC subfamily that plays a critical role in immune responses and inflammation. It is primarily produced by various immune cells, including monocytes, and is involved in the recruitment of leukocytes to sites of injury or infection. Research has indicated that CCL15 may have implications in several pathological conditions, particularly in cancer, where it can influence tumor microenvironments and contribute to tumor progression and metastasis. Furthermore, studies have suggested that CCL15 could serve as a potential biomarker for certain diseases and a therapeutic target in immunological therapies. The recombinant production of CCL15 protein has become pivotal in these investigations, allowing for the detailed study of its biological functions and mechanisms. Scientists utilize recombinant CCL15 in various experimental setups, including cell signaling assays, migration assays, and in vivo models to explore its effects on immune cell behavior and interactions. Understanding the functions and mechanisms of CCL15 can provide insights into its roles in health and disease, paving the way for novel therapeutic strategies that harness its properties to modulate immune responses in various clinical settings. Thus, the study of recombinant CCL15 protein not only enhances our understanding of chemokine biology but also contributes to the development of innovative approaches for managing inflammatory diseases and cancer.












