Analytical Data
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基因名
CCL17
- Application
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别名
CCL17；SCYA17；TARC；C-C motif chemokine 17
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q92583
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表达区间
24-94aa
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氨基酸序列
ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S
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分子量
8.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCL17, also known as Thymus and Activation-Regulated Chemokine (TARC), is a member of the CC chemokine family that plays a crucial role in immune responses, particularly in the recruitment and activation of T cells and dendritic cells. Initially identified for its expression in thymic and activated tissues, CCL17 has garnered attention for its involvement in various pathological conditions, including allergic reactions, asthma, and certain inflammatory diseases. The protein is primarily produced by activated dendritic cells and macrophages, highlighting its role in orchestrating immune responses during infections and autoimmune disorders. Given its significant involvement in immune regulation and potential implications in therapeutic applications, the recombinant production of CCL17 has become a focus of research. By developing recombinant CCL17 proteins, researchers aim to better understand its functional mechanisms and interactions within the immune system. Furthermore, exploring CCL17's role in different disease models could pave the way for novel diagnostic and therapeutic strategies, especially in treating immune-mediated diseases. Overall, the study of CCL17 as a recombinant protein is vital for advancing our understanding of immune dynamics and improving therapeutic interventions in various diseases linked to immune dysfunction.
