Analytical Data
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基因名
CCL18
- Application
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别名
CCL18；AMAC1；DCCK1；MIP4；C-C motif chemokine 18
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P55774
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表达区间
21-89aa
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氨基酸序列
AQVGTNKELCCLVYTSWQIPQKFIVDYSETSPQCPKPGVILLTKRGRQIC ADPNKKWVQKYISDLKLNA
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分子量
8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCL18, a member of the CC chemokine family, plays a significant role in immune responses and inflammation regulation. This chemokine is primarily produced by macrophages and dendritic cells and is known to be involved in various physiological and pathological processes, including allergy, asthma, and cancer progression. Its unique ability to attract various immune cells makes it a key player in the modulation of immune responses. Research has shown that elevated levels of CCL18 are associated with chronic inflammatory diseases, suggesting its potential as a biomarker for disease progression and therapeutic targets. The study of recombinant CCL18 protein has gained traction as researchers aim to elucidate its exact mechanisms of action and interactions with immune cells. Moreover, understanding its structure-function relationship is critical for the development of therapeutic interventions that may mitigate its role in diseases characterized by excessive inflammation or aberrant immune activation. As a result, CCL18 is not only a pivotal molecule for understanding immune regulation but also a promising candidate for novel therapeutic strategies, making it a focus of ongoing research in immunology and related fields.
