Cat: PA1000-9210

Recombinant Human CA6 Protein,His

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Analytical Data

  • 基因名

    CA6

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    CA6;C1orf149;CENP-28;EAF6;Chromatin modification-related Protein MEAF6

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P23280

  • 表达区间

    18-308aa

  • 氨基酸序列

    QHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEILDYLRRALN

  • 分子量

    41.0 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

CA6, or carbonic anhydrase 6, is a member of the carbonic anhydrase enzyme family that plays a crucial role in regulating pH and bicarbonate levels in biological systems. This enzyme is primarily expressed in the salivary glands and is involved in various physiological processes, including salivary bicarbonate secretion, which contributes to the maintenance of oral health. Recent studies have highlighted the significance of CA6 in various pathological conditions, such as autoimmune diseases and oral cancers, suggesting that alterations in its expression or activity may influence disease progression. Given its potential as a biomarker and therapeutic target, researchers have focused on recombinant CA6 proteins to explore their biochemical properties and interactions. The production of recombinant CA6 allows for detailed functional studies, including enzyme kinetics, substrate specificity, and structural analyses through techniques like X-ray crystallography. Understanding the molecular mechanisms underlying CA6 function and its role in disease can pave the way for developing novel diagnostic and therapeutic strategies. Furthermore, research into CA6 is also essential for exploring its evolutionary significance and functional diversity among different species, thereby contributing to a broader understanding of carbonic anhydrases in health and disease. Overall, the investigation of CA6 and its recombinant protein holds promise not only for advancing scientific knowledge but also for improving clinical outcomes in related health issues.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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