Analytical Data
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基因名
CCDC104
- Application
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别名
CCDC104；CCDC104；Cilia- and flagella-associated Protein 36
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96G28
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表达区间
1-342aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMAAEEED EVEWVVESIA GFLRGPDWSI PILDFVEQKC EVFDDEEESK LTYTEIHQEY KELVEKLLEG YLKEIGINED QFQEACTSPL AKTHTSQAIL QPVLAAEDFT IFKAMMVQKN IEMQLQAIRI IQERNGVLPD CLTDGSDVVS DLEHEEMKIL REVLRKSKEE YDQEEERKRK KQLSEAKTEE PTVHSSEAAI MNNSQGDGEH FAHPPSEVKM HFANQSIEPL GRKVERSETS SLPQKDLKIP GLEHASIEGP IANLSVLGTE ELRQREHYLK QKRDKLMSMR KDMRTKQIQN MEQKGKPTGE VEEMTEKPEM TAEEKQTLLK RRLLAEKLKE EVINK
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分子量
42 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCDC104, or Coiled-Coil Domain Containing 104, is a protein primarily studied for its role in the cellular processes that govern cilia formation and function. Cilia are essential for various physiological processes, including cell signaling, motility, and the development of organs. Dysfunction in cilia can lead to a group of genetic disorders known as ciliopathies, which are associated with a range of symptoms including developmental delays, organ malformation, and infertility. Research on CCDC104 has emerged as scientists seek to understand its specific functions and interactions within the ciliary assembly and maintenance pathways. Preliminary studies have suggested that CCDC104 may play a crucial role in the stabilization of ciliary structures and the regulation of protein transport to the cilium, highlighting its potential significance in both normal cellular physiology and disease mechanisms. As such, investigation into CCDC104 not only expands our understanding of ciliary biology but also underscores its potential as a target for therapeutic interventions in ciliopathy-related conditions. Understanding the molecular mechanisms mediated by CCDC104 could pave the way for novel strategies to address the challenges posed by these complex genetic disorders.
