Analytical Data
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基因名
CADM1
- Application
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别名
CADM1；IGSF4；IGSF4A；NECL2；Cell adhesion molecule 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BY67
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表达区间
45-374aa
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氨基酸序列
QNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKD SRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPP RNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEE WSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQ VHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTT TTTTTTTTTILTIITDSRAGEEGSIRAVDH
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分子量
39 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CADM1 (Cell Adhesion Molecule 1), also known as SynCAM or Necl-2, is a member of the immunoglobulin superfamily and plays a crucial role in cell adhesion processes, particularly in the nervous system. Its primary function is to facilitate cell-cell interactions, which are essential for neuronal development, synaptogenesis, and maintaining synaptic integrity. Recent studies have highlighted the involvement of CADM1 in various physiological and pathological conditions, including neurodevelopmental disorders, brain tumors, and autoimmune diseases. The interest in CADM1 has surged due to its potential as a therapeutic target, especially in the context of neurological diseases. The production of recombinant CADM1 proteins allows researchers to investigate its functional properties, structural characteristics, and interactions with other cellular molecules in detail. By employing techniques such as ELISA, Western blotting, and immunofluorescence, researchers can explore how CADM1 influences cell behavior, signal transduction, and disease progression. Furthermore, understanding the role of CADM1 in neuronal health and disease may lead to innovative strategies for therapeutic intervention, making it a significant focus of ongoing biomedical research.
