Analytical Data
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基因名
SOD4
- Application
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别名
SOD4；PGA2；SOD32；Cell surface superoxide dismutase [Cu-Zn] 4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O14618
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表达区间
1-274aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMASDSGNQGTLCTLEFAVQMTCQSCVDAVR KSLQGVAGVQDVEVHLEDQMVLVHTTLPSQEVQALLEGTGRQAVLKGMGS GQLQNLGAAVAILGGPGTVQGVVRFLQLTPERCLIEGTIDGLEPGLHGLH VHQYGDLTNNCNSCGNHFNPDGASHGGPQDSDRHRGDLGNVRADADGRAI FRMEDEQLKVWDVIGRSLIIDEGEDDLGRGGHPLSKITGNSGERLACGII ARSAGLFQNPKQICSCDGLTIWEERGRPIAGKGRKESAQPPAHL
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分子量
31 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SOD4, or superoxide dismutase 4, is a vital enzyme that plays a crucial role in protecting cells from oxidative stress by catalyzing the dismutation of superoxide radicals into oxygen and hydrogen peroxide. This enzyme is particularly important in various biological processes, including inflammation, aging, and neurodegenerative diseases, as excessive oxidative stress is linked to the pathology of conditions such as Alzheimer's and Parkinson's diseases. Research on SOD4 recombinant proteins has gained momentum due to their potential therapeutic applications in mitigating oxidative damage. By producing SOD4 through recombinant DNA technology, researchers can achieve high yields and ensure the protein's purity, facilitating detailed studies on its structure-function relationships and its protective mechanisms in biological systems. The investigation of SOD4's enzymatic activity, stability, and interaction with cellular components is pivotal for developing targeted drugs and therapeutic approaches. Furthermore, understanding the regulation of SOD4 expression and its role in cellular signaling pathways could illuminate new strategies for combating oxidative stress-related disorders. As the field of oxidative stress research expands, SOD4 recombinant proteins stand out as promising candidates for novel therapeutic interventions, underscoring the importance of continued research in this area.
