Analytical Data
-
基因名
BLVRB
- Application
-
别名
BLVRB；FLR；SCAN；Flavin reductase (NADPH)
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P30043
-
表达区间
2-206aa
-
氨基酸序列
AVKKIAIFG ATGQTGLTTL AQAVQAGYEV TVLVRDSSRL PSEGPRPAHV VVGDVLQAAD VDKTVAGQDA VIVLLGTRND LSPTTVMSEG ARNIVAAMKA HGVDKVVACT SAFLLWDPTK VPPRLQAVTD DHIRMHKVLR ESGLKYVAVM PPHIGDQPLT GAYTVTLDGR GPSRVISKHD LGHFMLRCLT TDEYDGHSTY PSHQYQ
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BLVRB, or Biliverdin Reductase B, is an enzyme that plays a crucial role in heme metabolism by catalyzing the reduction of biliverdin to bilirubin. This biochemical process is significant as bilirubin has antioxidant properties and contributes to the body's defense against oxidative stress. Recent studies have highlighted the potential implications of BLVRB in various physiological and pathological conditions, including its role in cellular signaling, inflammation, and neuroprotection. Research has indicated that dysregulation of BLVRB expression and activity may be linked to liver diseases, neurodegenerative disorders, and certain cancers, thereby making it a potential biomarker for disease progression and a target for therapeutic interventions. Understanding the structure and function of the BLVRB protein, as well as the regulatory mechanisms governing its action, is essential for delineating its biological significance and potential applications in clinical settings. As a result, ongoing research into BLVRB not only deepens our comprehension of heme metabolism but also paves the way for innovative strategies in treating diseases associated with oxidative stress and inflammation.
