Analytical Data
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Gene name
BLVRB
- Application
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Alternative Names
BLVRB；FLR；SCAN；Flavin reductase (NADPH)
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P30043
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Expression Region
2-206aa
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AA Sequence
AVKKIAIFG ATGQTGLTTL AQAVQAGYEV TVLVRDSSRL PSEGPRPAHV VVGDVLQAAD VDKTVAGQDA VIVLLGTRND LSPTTVMSEG ARNIVAAMKA HGVDKVVACT SAFLLWDPTK VPPRLQAVTD DHIRMHKVLR ESGLKYVAVM PPHIGDQPLT GAYTVTLDGR GPSRVISKHD LGHFMLRCLT TDEYDGHSTY PSHQYQ
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BLVRB, or Biliverdin Reductase B, is an enzyme that plays a crucial role in heme metabolism by catalyzing the reduction of biliverdin to bilirubin. This biochemical process is significant as bilirubin has antioxidant properties and contributes to the body's defense against oxidative stress. Recent studies have highlighted the potential implications of BLVRB in various physiological and pathological conditions, including its role in cellular signaling, inflammation, and neuroprotection. Research has indicated that dysregulation of BLVRB expression and activity may be linked to liver diseases, neurodegenerative disorders, and certain cancers, thereby making it a potential biomarker for disease progression and a target for therapeutic interventions. Understanding the structure and function of the BLVRB protein, as well as the regulatory mechanisms governing its action, is essential for delineating its biological significance and potential applications in clinical settings. As a result, ongoing research into BLVRB not only deepens our comprehension of heme metabolism but also paves the way for innovative strategies in treating diseases associated with oxidative stress and inflammation.
