Analytical Data
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Gene name
CNDP1
- Application
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Alternative Names
CNDP1；CN1；CPGL2；Beta-Ala-His dipeptidase
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96KN2
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Expression Region
27-507aa
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AA Sequence
SPSPPPALLE KVFQYIDLHQ DEFVQTLKEW VAIESDSVQP VPRFRQELFRMMAVAADTLQRLGARVASVDMGPQQLPDGQSLPIPPVILA ELGSDPTKGTVCFYGHLDVQPADRGDGWLTDPYVLTEVDGKLYGRGATDN KGPVLAWINAVSAFRALEQD LPVNIKFIIEGMEEAGSVALEELVEKEKDRFFSGVDYIVISDNLWISQRK PAITYGTRGNSYFMVEVKCRDQDFHSGTFGGILHEPMADLVALLGSLVDS SGHILVPGIYDEVVPLTEEEINTYKAIHLDLEEYRNSSRVEKFLFDTKEE ILMHLWRYPSLSIHGIEGAFDEPGTKTVIPGRVIGKFSIRLVPHMNVSAV EKQVTRHLEDVFSKRNSSNKMVVSMTLGLHPWIANIDDTQYLAAKRAIRT VFGTEPDMIRDGSTIPIAKMFQEIVHKSVVLIPLGAVDDGEHSQNEKINR WNYIEGTKLFAAFFLEMAQLHLEHHHHHH
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Molecular Weight
55 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CNDP1 (Carnosine Dipeptidase 1) is a gene that encodes a metallopeptidase enzyme, which plays a crucial role in the metabolism of dipeptides and is involved in the degradation of neuroprotective peptides such as carnosine and anserine. Research into CNDP1 has gained attention due to its potential implications in various physiological and pathological conditions, including diabetes, neurodegenerative diseases, and inflammatory processes. Notably, polymorphisms in the CNDP1 gene have been associated with diabetic nephropathy, highlighting its significance in kidney function and metabolic disorders. The study of CNDP1 recombinant proteins allows for a deeper understanding of its enzymatic activity and substrate specificity, facilitating the development of therapeutic strategies aimed at modulating its function. Additionally, the exploration of CNDP1's role in regulating oxidative stress and cellular homeostasis is critical for elucidating its contributions to health and disease. The recombinant form of CNDP1 can thus serve as a valuable tool for both basic research and clinical applications, particularly in identifying biomarkers for disease prediction and progression, as well as in exploring novel treatment avenues targeting metabolic and neurological conditions. Understanding the structural and functional dynamics of CNDP1 through recombinant technology not only expands our knowledge of its biochemical pathways but also provides insights into its therapeutic potential in mitigating diseases that impact millions globally.
