Analytical Data
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Gene name
Osbpl11
- Application
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Alternative Names
Short name: ORP-11 Short name: OSBP-related protein 11
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Species
Mouse
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8CI95
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Expression Region
1-751aa
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Molecular Weight
99.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Osbpl11, or Oxysterol-binding protein-like 11, is a member of the oxysterol-binding protein (OSBP) family, which plays crucial roles in lipid metabolism, cell signaling, and membrane trafficking. Research into Osbpl11 has gained prominence due to its potential implications in various physiological and pathological processes, including cholesterol homeostasis, inflammatory responses, and neurodegenerative diseases. The unique structure of Osbpl11, featuring both lipid-binding and regulatory domains, positions it as a pivotal player in cellular lipid signaling pathways. Investigating the recombinant expression of Osbpl11 provides insights into its functional mechanisms and interactions with other cellular components, offering a broader understanding of its role in health and disease. Recent studies have focused on the protein’s interactions with oxysterols and other lipid molecules, which may illuminate its contribution to cellular processes such as apoptosis and inflammation. As lipid dysregulation is linked to metabolic syndromes and diseases like atherosclerosis and Alzheimer’s, recombinant Osbpl11 serves as a valuable tool for elucidating its biological functions and developing targeted therapeutic strategies. Thus, the study of Osbpl11 not only enhances our understanding of lipid biology but also holds promise for advancing medical research aimed at treating lipid-related disorders.
