Analytical Data
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基因名
Osbpl11
- Application
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别名
Short name: ORP-11 Short name: OSBP-related protein 11
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种属
Mouse
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表达系统
E. coli
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标签
N- His-SUMO
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8CI95
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表达区间
1-751aa
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分子量
99.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Osbpl11, or Oxysterol-binding protein-like 11, is a member of the oxysterol-binding protein (OSBP) family, which plays crucial roles in lipid metabolism, cell signaling, and membrane trafficking. Research into Osbpl11 has gained prominence due to its potential implications in various physiological and pathological processes, including cholesterol homeostasis, inflammatory responses, and neurodegenerative diseases. The unique structure of Osbpl11, featuring both lipid-binding and regulatory domains, positions it as a pivotal player in cellular lipid signaling pathways. Investigating the recombinant expression of Osbpl11 provides insights into its functional mechanisms and interactions with other cellular components, offering a broader understanding of its role in health and disease. Recent studies have focused on the protein’s interactions with oxysterols and other lipid molecules, which may illuminate its contribution to cellular processes such as apoptosis and inflammation. As lipid dysregulation is linked to metabolic syndromes and diseases like atherosclerosis and Alzheimer’s, recombinant Osbpl11 serves as a valuable tool for elucidating its biological functions and developing targeted therapeutic strategies. Thus, the study of Osbpl11 not only enhances our understanding of lipid biology but also holds promise for advancing medical research aimed at treating lipid-related disorders.
