Cat: PA1000-323DB

Recombinant Human BEND6 Protein,His

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Analytical Data

  • Gene name

    BEND6

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    BEND6;C6orf65;BEN domain-containing Protein 6

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q5SZJ8

  • Expression Region

    1-279aa

  • AA Sequence

    MGSSHHHHHH SSGLVPRGSH MGSMQKIVQT DEITNTQAFR KGKRKRTETM DSENANSDMD KGQRDPYSGN AFLPGESSSE DEEPLAELSK EELCAKIKSL KEKLTNTRKE NSRLRQSLVM LQVLPQAVTQ FEELVGMAEA LLKGGGTMST SASTLWRATN NSSPDSFAST CSNSNSNSSS PVSLKPEEEH QTDEKQFQIE KWQIARCNKS KPQKFINDLM QVLYTNEYMA THSLTGAKSS TSRDKAVKPA MNQNEVQEII GVTKQLFPNT DDVSIRRMIG QKLNNCTKKP NLSKNLNSQD IK

  • Molecular Weight

    34 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

BEND6, a member of the BEND (bromodomain and extra-terminal domain) family of proteins, has garnered significant attention in recent research due to its potential roles in gene regulation and chromatin remodeling. This protein is characterized by the presence of multiple protein interaction domains, which suggest that it may participate in various cellular processes, including transcriptional regulation and signal transduction. Studies have indicated that BEND6 is involved in developmental pathways and may contribute to oncogenesis when dysregulated. With its implications in critical biological mechanisms, understanding the structure, function, and regulatory networks involving BEND6 can provide insights into its role in health and disease. Recent advancements in proteomic techniques and molecular biology have facilitated the exploration of BEND6's interactions with other proteins and its influence on the epigenetic landscape, highlighting its potential as a therapeutic target in cancer and other disorders linked to gene misregulation. As research continues, elucidating the precise functions and mechanisms of BEND6 will be pivotal in uncovering its contributions to cellular homeostasis and disease pathology.

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