Analytical Data
-
Gene name
map-1
- Application
-
Alternative Names
Peptidase M (MAP 1) (MetAP 1) (mapA)
-
Species
Mycobacterium tuberculosis
-
Source
E. coli
-
Tag
N- His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P9WK20
-
Expression Region
1-266aa
-
Molecular Weight
32.9 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MAP-1, or microtubule-associated protein 1, is a crucial component in the regulation of microtubule dynamics and stability in neuronal cells. Research into MAP-1 has gained significant momentum due to its essential role in neuronal development, plasticity, and the pathogenesis of neurodegenerative diseases. The MAP-1 family, particularly the MAP-1A and MAP-1B isoforms, contribute to the formation and stabilization of microtubules, which are vital for intracellular transport and the maintenance of cell structure. Disruptions in MAP-1 function or expression have been linked to various neurological disorders, including Alzheimer's disease and schizophrenia, where abnormal microtubule dynamics may contribute to synaptic dysfunction and cognitive decline. Recent studies have focused on elucidating the molecular mechanisms by which MAP-1 interacts with microtubules and other cellular components, as well as its potential as a therapeutic target for neurodegenerative conditions. Understanding the complex regulatory roles of MAP-1 in the neuronal cytoskeleton may pave the way for innovative strategies to enhance neuronal resilience and promote recovery in affected individuals. As a result, the exploration of MAP-1 functions and its implications in both health and disease remains a vibrant and critical area of neuroscience research.
