Analytical Data
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基因名
ADCY10
- Application
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别名
ADCY10;SAC;Adenylate cyclase type 10
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96PN6
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表达区间
全长
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氨基酸序列
full
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ADCY10 (Adenylate Cyclase 10) is a member of the adenylate cyclase family, which is crucial for the synthesis of cyclic adenosine monophosphate (cAMP), a vital second messenger involved in various cellular signaling pathways. The research on ADCY10 has gained traction due to its potential role in mediating responses to hormones, neurotransmitters, and other signaling molecules, influencing physiological processes such as mood regulation, metabolism, and cardiovascular function. Dysregulation of ADCY10 has been implicated in several pathological conditions, including mood disorders and cardiovascular diseases. Thus, understanding the structure and function of the ADCY10 protein is key for developing targeted therapies. Recent advancements in recombinant protein technology have enabled the production of purified ADCY10, facilitating detailed biophysical characterization and investigation of its enzymatic activity. This research also aims to explore the interaction of ADCY10 with various G-protein coupled receptors (GPCRs) and its downstream signaling pathways, providing insights into its physiological and pathological roles. Consequently, the study of ADCY10 not only enhances our comprehension of cAMP signaling but also opens avenues for novel therapeutic interventions in diseases associated with its dysfunction.












