Analytical Data
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基因名
KLF1
- Application
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别名
Erythroid krueppel-like transcription factor (EKLF) (EKLF)
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种属
Human
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表达系统
E. coli
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标签
N- His-B2M
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q13351
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表达区间
1-362aa
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分子量
52.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KLF1 (Krüppel-like factor 1), also known as EKLF (erythroid Krüppel-like factor), is a transcription factor predominantly expressed in erythroid lineages, playing a crucial role in the regulation of erythropoiesis. It is involved in the activation of globin genes and the development of red blood cells by maintaining the balance between cell proliferation and differentiation. Dysregulation of KLF1 expression has been associated with various hematological disorders, including congenital anemias and other blood-related pathologies. The study of KLF1 recombinant proteins has emerged as a significant area of interest in molecular biology and biotechnology, as these proteins can be used to elucidate the mechanisms of gene regulation in erythropoiesis and to explore potential therapeutic applications. By employing recombinant DNA technology, researchers can produce KLF1 in a controlled environment, enabling the investigation of its functional properties, interaction with other proteins, and influence on gene expression. Additionally, understanding the structural and functional characteristics of KLF1 may facilitate the development of novel strategies for treating anemic conditions and other disorders linked to erythropoiesis. As research progresses, the insights gained from KLF1 recombinant protein studies could pave the way for innovative therapeutic interventions and deepen our understanding of erythroid biology.
