Analytical Data
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基因名
GNA13
- Application
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别名
G alpha 13; G alpha-13; G-protein subunit alpha-13; GNA13; GNA13_HUMAN; Guanine nucleotide binding protein (G protein) alpha 13; Guanine nucleotide binding protein alpha 13 subunit; Guanine nucleotide-binding protein subunit alpha-13
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种属
Human
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q14344
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表达区间
1-377aa
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分子量
48.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GNA13, a member of the Rho family of small GTPases, plays a crucial role in various cellular processes, including cytoskeletal dynamics, cell migration, and signal transduction. Its significance has gained attention in cancer research, as altered GNA13 activity is associated with tumorigenesis and metastasis. Researchers have been particularly focused on the role of GNA13 in regulating lymphocyte function and its implications in immune response and inflammation. The reconstitution of GNA13 in vitro has been pursued to better understand its molecular mechanisms and interactions with downstream effectors. Furthermore, recombinant GNA13 proteins can serve as valuable tools for elucidating the pathways involved in Rho GTPase signaling and exploring potential therapeutic targets. Advances in recombinant protein technology have enabled the production of GNA13 with high purity and activity, facilitating detailed biochemical and structural studies. Investigating GNA13's function may unveil new insights into its contribution to disease progression and identify potential avenues for therapeutic intervention.
