Analytical Data
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Gene name
PLIN4
- Application
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Alternative Names
PLIN4；KIAA1881；Perilipin-4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96Q06
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Expression Region
308-418aa
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AA Sequence
GVDTSKTVLTGTKDTVCSGVTGAMNVAKGTIQTGVDTTKTVLTGTKNTVCSGVTGAVNLAKEAIQGGLDTTKSMVMGTKDTMSTGLTGAANVAKGAMQTGLNTTQNIATGT
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Molecular Weight
12.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PLIN4 (perilipin 4) is a member of the perilipin family of proteins, which play a crucial role in lipid storage and metabolism. Research has increasingly focused on PLIN4 due to its involvement in the regulation of lipid droplets, which are essential cellular organelles that store neutral lipids and are implicated in various metabolic processes. PLIN4 has been identified as a key player in adipocyte differentiation and is thought to influence the mobilization of lipids during metabolic stress. Moreover, dysregulation of lipid metabolism linked to PLIN4 is associated with obesity, type 2 diabetes, and other metabolic disorders, making it a significant target for therapeutic interventions. Advances in recombinant protein technology have enabled the production of PLIN4 to study its structure and function in detail, revealing insights into its interactions with other lipid-associated proteins and its role in cellular signaling pathways. Understanding PLIN4's mechanism of action could provide valuable information for developing strategies to combat metabolic diseases related to impaired lipid homeostasis. As research continues to unveil the complexities of this protein, it holds promise for elucidating new aspects of lipid metabolism and potential clinical applications in treating metabolic syndromes.
